This molecule is directly associated with the expression of the cellular prion protein located on the surface of nerve cells. The research, conducted by the Institute for Bioengineering of Catalonia, paves the way for early detection of Alzheimer's disease. A new study conducted by the Molecular

Clinical relevance of miRNAs as biomarkers is growing due to their stability and detection in biofluids. This study has identified miR-519a-3p as a potential early biomarker for Alzheimer’s, linked to prion protein expression. This molecule is directly associated with the expression of the cellular prion protein located on the surface of nerve cells. miR-519a-3p may potentially be used as a biomarker of preclinical stages of the disease.

https://www.sciencedirect.com/science/article/pii/S0925443924001765?via%3Dihub (open access)

  • originalucifer@moist.catsweat.com
    17·
    23 days ago

    In our study, we compared the levels of this biomarker in samples from other tauopathies and Parkinson’s disease, confirming that the changes in miR-519a-3p are specific to Alzheimer’s disease,” said IBEC senior researcher Rosalina Gavín, UB associate professor and co-leader of the study.

    coooool!