Usually microtransactions have such a low real price that it wouldn’t make sense to make the bank transaction for just a single skin or whatever. I think you’d just end up with bundles instead where there’s a single thing you actually want with a bunch of bullshit attached to justify a higher asking price.
I play it with hotas and it works fine. You’ll absolutely still want to keep a keyboard and mouse handy though because the RTS/management half of the game is really not that well controlled with a flight stick.